Goerz G, Hammer G
Dermatologica. 1983 Jun;166(6):316-8. doi: 10.1159/000249898.
A female patient with porphyria cutanea tarda (PCT) clinically cured by a low-dose chloroquine treatment showed neither exacerbation of the disease nor an increased excretion of urinary porphyrins during pregnancy. The role of estrogens and gestagens as clinical manifestation factors of PCT is discussed. According to our observation the porphyrogenic effect of the estrogens seems to have been overestimated.
一名迟发性皮肤卟啉症(PCT)女性患者经低剂量氯喹治疗后临床治愈,孕期疾病未加重,尿卟啉排泄也未增加。本文讨论了雌激素和孕激素作为PCT临床表现因素的作用。根据我们的观察,雌激素的卟啉原效应似乎被高估了。