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腮腺恶性上皮性肿瘤的术后放疗

Postoperative irradiation in malignant epithelial tumors of the parotid.

作者信息

McNaney D, McNeese M D, Guillamondegui O M, Fletcher G H, Oswald M J

出版信息

Int J Radiat Oncol Biol Phys. 1983 Sep;9(9):1289-95. doi: 10.1016/0360-3016(83)90259-6.

DOI:10.1016/0360-3016(83)90259-6
PMID:6885541
Abstract

From 1954 through 1979, 77 patients with malignant tumors of the parotid gland were referred from the Department of Head and Neck Surgery for postoperative irradiation. The analysis has been made by grouping the patients according to the estimated amount of disease left after the surgical procedure and by the histological types. There were no local failures in the low-grade tumors, and there were 6 in the 63 patients with high-grade tumors. With gross residual disease or potential residual disease the patients received slightly higher doses than those without. Although there were only 6 failures in the various histological types, there was perhaps a trend to more failures in the adenocarcinomas. There was no difference in the failure rates in patients having had a total resection of the facial nerve or partial resection or no resection. The preferred treatment has been a combination of 20 MeV photons and 18 MeV electrons. Five neck failures were essentially a result of lack of elective irradiation of the neck. Severe complications appeared only in the patients irradiated either for gross residual disease or excision of a recurrence with a high risk of widespread microscopic residual disease.

摘要

1954年至1979年期间,头颈外科将77例腮腺恶性肿瘤患者转诊至放疗科进行术后放疗。通过根据手术切除后估计的疾病残留量以及组织学类型对患者进行分组来进行分析。低级别肿瘤无局部复发,63例高级别肿瘤患者中有6例复发。有大体残留疾病或潜在残留疾病的患者接受的剂量略高于无残留疾病的患者。尽管不同组织学类型中仅有6例复发,但腺癌可能有更多复发的趋势。面神经全切、部分切除或未切除的患者复发率无差异。首选治疗方法是20兆电子伏光子和18兆电子伏电子联合治疗。5例颈部复发主要是由于未进行颈部选择性放疗。严重并发症仅出现在因大体残留疾病或切除有广泛微小残留疾病高风险的复发病灶而接受放疗的患者中。

相似文献

1
Postoperative irradiation in malignant epithelial tumors of the parotid.腮腺恶性上皮性肿瘤的术后放疗
Int J Radiat Oncol Biol Phys. 1983 Sep;9(9):1289-95. doi: 10.1016/0360-3016(83)90259-6.
2
High-grade malignancies of the parotid gland: effective use of planned combined surgery and irradiation.腮腺高级别恶性肿瘤:计划性联合手术与放疗的有效应用。
Laryngoscope. 1985 Sep;95(9 Pt 1):1059-63.
3
An analysis of facial nerve function in irradiated and unirradiated facial nerve grafts.照射及未照射面神经移植物的面神经功能分析
Int J Radiat Oncol Biol Phys. 2000 Oct 1;48(3):737-43. doi: 10.1016/s0360-3016(00)00721-5.
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Long-term outcomes and quality of life of 186 patients with primary parotid carcinoma treated with surgery and radiotherapy at the Daniel den Hoed Cancer Center.丹尼尔·丹霍德癌症中心 186 例原发性腮腺癌患者手术联合放疗的长期疗效及生活质量。
Int J Radiat Oncol Biol Phys. 2012 Sep 1;84(1):189-95. doi: 10.1016/j.ijrobp.2011.11.045. Epub 2012 Feb 11.
5
Carcinoma of the parotid gland.腮腺癌
Am J Surg. 2003 Jul;186(1):57-62. doi: 10.1016/s0002-9610(03)00105-3.
6
Radiotherapy for parotid cancer.
Ann Surg Oncol. 1994 Nov;1(6):468-72. doi: 10.1007/BF02303611.
7
Postoperative radiotherapy for malignant tumors of the parotid gland.
Int J Radiat Oncol Biol Phys. 1997 Jan 1;37(1):79-85. doi: 10.1016/s0360-3016(96)00464-6.
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Malignant parotid tumors in 110 consecutive patients: treatment results and prognosis.110例连续性腮腺恶性肿瘤患者:治疗结果与预后
Laryngoscope. 1992 Sep;102(9):1064-9. doi: 10.1288/00005537-199209000-00019.
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Acinic cell carcinoma of the parotid gland: review and management.腮腺腺泡细胞癌:综述与治疗
J Otolaryngol. 1991 Aug;20(4):262-6.
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Conservative parotidectomy for the treatment of parotid cancers.保守性腮腺切除术治疗腮腺癌。
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引用本文的文献

1
PAROTOID TUMOURS: A STUDY OF 65 CASES.腮腺肿瘤:65例病例研究
Med J Armed Forces India. 1999 Jan;55(1):35-37. doi: 10.1016/S0377-1237(17)30310-6. Epub 2017 Jun 26.
2
Carcinoma of the major salivary glands. analysis of the role of radiation therapy.大唾液腺癌。放射治疗作用的分析。
Indian J Otolaryngol Head Neck Surg. 1999 Oct;51(4):19-22. doi: 10.1007/BF03022708.
3
Radiotherapy for parotid cancer.
Ann Surg Oncol. 1994 Nov;1(6):468-72. doi: 10.1007/BF02303611.
4
Carcinoma of the major salivary glands.大唾液腺癌
Ann R Coll Surg Engl. 1992 May;74(3):186-91.