细胞铺展的动力学分析。I. 曲线的理论与建模

Kinetic analysis of cell spreading. I. Theory and modelling of curves.

作者信息

Bardsley W G, Aplin J D

出版信息

J Cell Sci. 1983 May;61:365-73. doi: 10.1242/jcs.61.1.365.

DOI:10.1242/jcs.61.1.365

Abstract

The spreading of cells on suitably treated surfaces is briefly discussed and the need to analyse this phenomenon numerically is emphasized. Possible mathematical models for fitting experimental data are classified as statistical, kinetic or empirical and examples of each of these types are given. A possible protocol for analysing cell spreading kinetics and determining goodness of fit and parameter redundancy is presented.

摘要

简要讨论了细胞在经过适当处理的表面上的铺展情况，并强调了对这一现象进行数值分析的必要性。适用于拟合实验数据的可能数学模型被分类为统计模型、动力学模型或经验模型，并给出了每种类型的示例。提出了一种分析细胞铺展动力学以及确定拟合优度和参数冗余度的可能方案。