稀释抑制因子，小家鼠中的一种新的抑制基因。

Dilute suppressor, a new suppressor gene in the house mouse.

作者信息

Sweet H O

出版信息

J Hered. 1983 Jul-Aug;74(4):305-6. doi: 10.1093/oxfordjournals.jhered.a109794.

DOI:10.1093/oxfordjournals.jhered.a109794

Abstract

Dilute suppressor, dsu, a new fully penetrant autosomal recessive mutation, acts by restoring melanocytes of homozygous dilute (d/d) mice to normal shape and almost normal number. This action creates a nondilute appearing coat color in dilute mice. Dilute suppressor is located on chromosome 1 linked to isocitrate dehydrogenase (Idh-I) with 6.25 +/- 3.49 percent recombination, and is not linked to dilute, which is on chromosome 9.

摘要

稀释抑制基因（dsu）是一种新的完全显性常染色体隐性突变基因，其作用是使纯合稀释（d/d）小鼠的黑素细胞恢复正常形态和接近正常数量。这种作用使稀释小鼠呈现出非稀释的毛色。稀释抑制基因位于1号染色体上，与异柠檬酸脱氢酶（Idh-I）连锁，重组率为6.25 +/- 3.49%，与位于9号染色体上的稀释基因不连锁。