Pagnanelli D M, Naradzay J F, Pait T G, Rizzoli H V, Kobrine A I
J Neurosurg. 1983 Sep;59(3):510-3. doi: 10.3171/jns.1983.59.3.0510.
The authors have compared the vascular endothelial damage caused by blunt-tipped microvascular needles as reported previously with that of sharp cutting-edged needles of comparable size. The same four distinct vascular lesions were found with cutting-edged needles as with the blunt-tipped needles. Even though one experimenter made all of the lesions, and all of the tissue was handled in the same fashion, there was much variation in the extent of the intimal damage. Overall, cutting-edged needles produced slightly less intimal tearing and platelet aggregation than blunt-tipped needles, but the difference was not striking.
作者将先前报道的钝头微血管针造成的血管内皮损伤与尺寸相当的锋利刃口针造成的损伤进行了比较。锋利刃口针造成的血管病变与钝头针相同,共有四种不同的病变。尽管所有损伤均由同一名实验者造成,且所有组织的处理方式相同,但内膜损伤程度仍存在很大差异。总体而言,锋利刃口针造成的内膜撕裂和血小板聚集略少于钝头针,但差异并不显著。