Berger A, Millesi H
Clin Orthop Relat Res. 1978 Jun(133):49-55.
By avoiding tension and securing anatomical neurorrhaphy, regeneration of nerve is obtainable. When the gap exceeds a certain limit, the only way to avoid tension is the use of grafts. Experience in animal experiments and clinical practice has demonstrated that regenerating axons can cross 2 optimal suture lines much more easily than one sub-standard one. For bridging a gap autografts are used, because in autografts the fascicular pattern is preserved and its Swann cells survive. With the interfascicular technique the dissection of the nerve stumps proceeds from normal to abnormal tissues and the epineurium is resected. The coaptation must be exact so that the grafts cover the whole cross sectional area of the fascicle. All this can be achieved by the use of one 10--0 or 11--0 nylon suture. The clinical results show that in the median nerve 82%, in the ulnar 80% and in the radial nerve 92% of good functional results can be obtained. Also in brachial plexus injuries the interfascicular nerve grafting procedure opened new ways. Therefore interfascicular nerve grafting, using autografts in cases of nerve repair, where a gap may occur, currently is the method of choice.
通过避免张力并确保解剖学神经缝合,可实现神经再生。当间隙超过一定限度时,避免张力的唯一方法是使用移植体。动物实验和临床实践经验表明,再生轴突穿过两条最佳缝合线比穿过一条不合标准的缝合线要容易得多。为了桥接间隙,使用自体移植体,因为在自体移植体中,束状结构得以保留且施万细胞存活。采用束间技术时,神经残端的解剖从正常组织向异常组织进行,同时切除神经外膜。吻合必须精确,以便移植体覆盖束的整个横截面积。所有这些都可以通过使用一根10 - 0或11 - 0尼龙缝线来实现。临床结果表明,正中神经损伤采用该方法后,82%可获得良好功能结果;尺神经损伤为80%;桡神经损伤为92%。在臂丛神经损伤中,束间神经移植手术也开辟了新途径。因此,在可能出现间隙的神经修复病例中,使用自体移植体的束间神经移植目前是首选方法。