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小鼠的听觉发育:中耳的结构成熟

Auditory development in the mouse: structural maturation of the middle ear.

作者信息

Huangfu M, Saunders J C

出版信息

J Morphol. 1983 Jun;176(3):249-59. doi: 10.1002/jmor.1051760302.

DOI:10.1002/jmor.1051760302
PMID:6887258
Abstract

The development of middle-ear structures in the mouse was examined in nine groups of pups between 1 and 45 days of age. The area of the tympanic membrane (pars tensa and pars flaccida), the length of the lever arms of the malleus and incus, the surface area of the oval window, and the volume of the bulla all showed systematic changes during neonatal life. The area of the oval window reached maturity first and the lever arms achieved 90% of their adult size on day 11. The tympanic membrane achieved the same criterion on day 18. These data help us further to understand the processes that contribute to the functional ontogeny of the middle ear.

摘要

对1至45日龄的九组幼鼠的中耳结构发育进行了研究。鼓膜(紧张部和松弛部)的面积、锤骨和砧骨杠杆臂的长度、卵圆窗的表面积以及鼓室的体积在新生儿期均呈现出系统性变化。卵圆窗的面积最先达到成熟,杠杆臂在第11天达到其成年大小的90%。鼓膜在第18天达到相同标准。这些数据有助于我们进一步了解促成中耳功能个体发育的过程。

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