Cohen Y E, Bacon C K, Saunders J C
Department of Bioengineering, University of Pennsylvania.
Hear Res. 1992 Oct;62(2):187-93. doi: 10.1016/0378-5955(92)90185-p.
Middle-ear structural ontogeny was examined in 12 age groups of Mongolian gerbils between 2 and 42 days after birth. Measurements of tympanic membrane surface area; depth of the tympanic membrane cone; the lengths of the malleus and incus long processes; and stapes footplate, annular space, and oval window areas were obtained using video micrographs and computer digitization techniques. The incus long process matured first at 3.5 days after birth, while the pars flaccida surface area was the last middle-ear variable studied to reach adult size (26 days after birth). The incus long process increased its length by 30% from 0.5 mm to 0.65 mm. The malleus long process, however, demonstrated much more relative growth (47%). Pars tensa area expanded from 6.35 mm2 at two days after birth to its adult size of 16.9 mm2 and the stapes footplate expanded by 50%. The developmental changes observed in middle-ear anatomy are then discussed with regard to their contribution to the functional maturation of both the middle ear and more central auditory function.
对出生后2至42天的12个年龄组蒙古沙鼠的中耳结构个体发育进行了研究。使用视频显微照片和计算机数字化技术测量鼓膜表面积、鼓膜锥深度、锤骨和砧骨长突长度，以及镫骨足板、环状间隙和椭圆窗面积。砧骨长突在出生后3.5天首先成熟，而松弛部表面积是最后一个达到成年大小（出生后26天）的中耳变量。砧骨长突长度从0.5毫米增加到0.65毫米，增长了30%。然而，锤骨长突的相对生长幅度更大（47%）。紧张部面积从出生后两天的6.35平方毫米扩展到成年大小的16.9平方毫米，镫骨足板扩大了50%。随后讨论了中耳解剖结构中观察到的发育变化对中耳和更高级中枢听觉功能功能成熟的贡献。
