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营养与感染的相互作用:锌缺乏对鼠锥虫感染中免疫球蛋白水平的影响。

Interaction of nutrition and infection: effect of zinc deficiency on immunoglobulin levels in trypanosoma musculi infection.

作者信息

Lee C M, Humphrey P A, Aboko-Cole G F

出版信息

J Natl Med Assoc. 1983 Jul;75(7):677-82.

Abstract

Accumulative evidence in the scientific literature relating malnutrition and susceptibility to infection in human beings and animals has contributed significantly to the understanding of the maladies among the malnourished of the world. In the dispensation of health care systems around the world, little or no emphasis has been placed on trace-element nutrition. This paper adds to the available evidence by using a metabolic imbalance technique to investigate the effects zinc deficiency exert on the course of a parasitic infection. A model composed of zinc-deficient mice and Trypanosoma musculi was used to study changes in serum immunoglobulins.

摘要

科学文献中有关人类和动物营养不良与感染易感性的累积证据,对理解全球营养不良人群的疾病起到了重要作用。在世界各地的卫生保健系统分配中,对微量元素营养几乎没有给予重视。本文通过运用代谢失衡技术来研究锌缺乏对寄生虫感染病程的影响,从而增加了现有证据。使用由缺锌小鼠和鼠锥虫组成的模型来研究血清免疫球蛋白的变化。

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Trypanosoma musculi infections in complement-deficient mice.
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本文引用的文献

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Trace metals in human and animal health.人类与动物健康中的痕量金属。
J Hum Nutr. 1981 Feb;35(1):37-48. doi: 10.3109/09637488109143484.
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Biochemical, skeletal and allometric changes due to zinc deficiency in the baby pig.
J Nutr. 1968 Jun;95(2):278-86. doi: 10.1093/jn/95.2.278.

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