Wilson P D, Dixon J S, Brown A D, Gosling J A
J Urol. 1983 Oct;130(4):802-5. doi: 10.1016/s0022-5347(17)51469-x.
Specimens of the posterior pubo-urethral ligament were taken from 10 continent females (7 at post mortem and 3 at gynaecological surgery) and from 9 genuine stress incontinent patients. They were examined and compared using light and electron microscopy and neuro-histochemistry. The morphology of all specimens was similar in that they contained dense connective tissue elements enclosing smooth muscle bundles which were associated with numerous nerves, the enzyme content and fine structure of which were similar to those believed to represent cholinergic autonomic nerves. There was no difference in the morphology, histochemistry and fine structure of the specimens of the ligaments from the control and incontinent patients. Therefore, it is suggested that altered morphology of the posterior pubo-urethral ligaments is unlikely to be an etiological factor in genuine stress incontinence. It is postulated that the ligaments may play a role in stabilising the proximal urethra or assist in bladder-neck opening during voiding.
从10名控尿女性（7例尸检病例和3例妇科手术病例）以及9例真性压力性尿失禁患者身上获取耻骨后尿道韧带标本。运用光学显微镜、电子显微镜及神经组织化学技术对这些标本进行检查与对比。所有标本的形态相似，均含有致密结缔组织成分，包绕着平滑肌束，且这些平滑肌束与众多神经相连，这些神经的酶含量及精细结构与被认为代表胆碱能自主神经的神经相似。对照组和尿失禁患者韧带标本的形态、组织化学及精细结构并无差异。因此，提示耻骨后尿道韧带形态改变不太可能是真性压力性尿失禁的病因。据推测，这些韧带可能在稳定尿道近端或排尿时协助膀胱颈开放方面发挥作用。
