Hassouna M, Galeano C, Lamarche J, Abdel-Rahman M, Elhilali M M
J Urol. 1983 Oct;130(4):806-10. doi: 10.1016/s0022-5347(17)51470-6.
Multiple sclerosis-like disease was induced in 18 rabbits by immunization with guinea pig spinal cord. The urodynamic studies conducted in the immunized rabbits showed a significantly lower maximal urethral pressure and a lower bladder capacity than those in the control group. We compared the urodynamic, clinical and histopathological parameters in the immunized rabbits. We conclude that the rabbit is an acceptable model for studying the bladder and urethral dynamics during various phases of experimental allergic encephalomyelitis (multiple sclerosis-like disease).
通过用豚鼠脊髓免疫，在18只兔子身上诱发了类似多发性硬化症的疾病。对免疫后的兔子进行的尿动力学研究显示，其最大尿道压力显著低于对照组，膀胱容量也低于对照组。我们比较了免疫兔子的尿动力学、临床和组织病理学参数。我们得出结论，兔子是研究实验性变应性脑脊髓炎（类似多发性硬化症的疾病）各阶段膀胱和尿道动力学的可接受模型。
