Kano T, Kumashiro R, Masuda H, Okamura T, Inokuchi K
Jpn J Surg. 1983 Mar;13(2):106-11. doi: 10.1007/BF02469529.
Between 1964 and 1981, 100 in-patients with recurrent gastric carcinoma following curative resection were investigated in the Second Department of Surgery, Kyushu University Hospital. The disease-free interval after initial operation and the advancement of the carcinoma correlated. The mean disease free interval of cases with local recurrence was 4 years and 1 month, that is 2 years longer than in cases of peritoneal dissemination or hematogenous metastasis. The disease free interval and the survival time after recurrence also correlated. Patients with a relapse more than 2 years after initial operation survived statistically longer than did those with a relapse in less than 2 years (p less than 0.01). One and 2 year survival rates after recurrence in the second resection group was 41.4 per cent and 17.2 per cent, respectively. Almost all patients in the other group died within one year after recurrence. The average survival in patients on a combination of chemotherapy and resection of the recurrent tumor was about 2 years and longer than in cases of resection but without chemotherapy.
1964年至1981年间,九州大学医院第二外科对100例根治性切除术后复发性胃癌的住院患者进行了调查。初次手术后的无病间期与癌的进展相关。局部复发患者的平均无病间期为4年零1个月,比腹膜播散或血行转移患者长2年。无病间期与复发后的生存时间也相关。初次手术后复发超过2年的患者在统计学上比复发少于2年的患者存活时间更长(p小于0.01)。二次切除组复发后的1年和2年生存率分别为41.4%和17.2%。另一组几乎所有患者在复发后1年内死亡。接受化疗联合复发性肿瘤切除的患者的平均生存期约为2年,比仅行切除但未化疗的患者更长。