Karpman V L, Belotserkovskii Z B, Liubina B G, Tiĭdus Ia Kh
Kardiologiia. 1983 Jun;23(6):106-9.
The Frank-Starling mechanism was investigated in 88 athletes exposed to physical stress and was shown to operate under physical stress in athletes with ventricular cavities of normal or moderately increased size. In athletes with physiological ventricular dilatation as a result of endurance training (over 160 ml in ultimate diastolic volume), the Frank-Starling mechanism is not normally triggered under stress: increased cardiac output is provided by greater basal blood volume reserve. With ultimate diastolic volumes of 115-159 ml, the Frank-Starling mechanism provides an optimum increase in peak stroke volume. The effectiveness of the heterometric mechanism activated by physical stress in subjects with small ultimate diastolic volumes is not sufficient as additive reserve volume cannot be increased essentially.
对88名承受身体应激的运动员的弗兰克 - 斯塔林机制进行了研究，结果表明，在心室腔大小正常或适度增大的运动员中，该机制在身体应激状态下起作用。在因耐力训练导致生理性心室扩张（舒张末期容积超过160毫升）的运动员中，应激状态下通常不会触发弗兰克 - 斯塔林机制：心输出量的增加是由更大的基础血容量储备提供的。当舒张末期容积为115 - 159毫升时，弗兰克 - 斯塔林机制能使每搏输出量峰值实现最佳增加。对于舒张末期容积较小的受试者，身体应激激活的异长调节机制的有效性不足，因为附加储备量基本无法增加。
