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熔融石英毛细管柱与氮磷检测器联用在一例人体过量服用案件中对可待因和乙基吗啡进行毒理学测定的应用。

Application of the combined use of fused silica capillary columns and NPD for the toxicological determination of codeine and ethylmorphine in a human overdose case.

作者信息

Demedts P, De Waele M, Van der Verren J, Heyndrickx A

出版信息

J Anal Toxicol. 1983 May-Jun;7(3):113-5. doi: 10.1093/jat/7.3.113.

DOI:10.1093/jat/7.3.113
PMID:6887789
Abstract

The applicability of capillary gas chromatography to the toxicological analysis of extracts of human tissue samples was investigated for codeine and ethylmorphine in a case of drug overdose. After column extraction, the samples were injected onto a fused silica capillary column, using a direct injection technique. The nitrogen-phosphorus detector provided excellent stability and sensitivity without the need for extensive clean-up procedures.

摘要

在一例药物过量案例中,研究了毛细管气相色谱法在人体组织样品提取物中可待因和乙基吗啡毒理学分析中的适用性。柱萃取后,采用直接进样技术将样品注入熔融石英毛细管柱。氮磷检测器无需大量净化程序即可提供出色的稳定性和灵敏度。

相似文献

1
Application of the combined use of fused silica capillary columns and NPD for the toxicological determination of codeine and ethylmorphine in a human overdose case.熔融石英毛细管柱与氮磷检测器联用在一例人体过量服用案件中对可待因和乙基吗啡进行毒理学测定的应用。
J Anal Toxicol. 1983 May-Jun;7(3):113-5. doi: 10.1093/jat/7.3.113.
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[Photoelectrocolorimetric determination of codeine and ethylmorphine in drug mixtures].[药物混合物中可待因和乙基吗啡的光电比色测定]
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引用本文的文献

1
Ethylmorphine concentrations in human samples in an overdose case.一起过量用药案例中人体样本中的乙基吗啡浓度。
Arch Toxicol. 1994;68(3):210-1. doi: 10.1007/s002040050057.