• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

致命阿片类药物过量。硅烷化后通过气相色谱-质谱联用仪对血样中各种代谢物进行毒理学鉴定。

Fatal opiates overdose. Toxicological identification of various metabolites in a blood sample by GC-MS after silylation.

作者信息

Balíková M, Maresová V

机构信息

Institute for Toxicology and Forensic Chemistry, 1st Medical Faculty and Hospital, Charles University, Prague, Czech Republic.

出版信息

Forensic Sci Int. 1998 Jun 22;94(3):201-9. doi: 10.1016/s0379-0738(98)00077-2.

DOI:10.1016/s0379-0738(98)00077-2
PMID:9717273
Abstract

A fatal opiates overdose, where ethylmorphine, hydrocodone, dihydrocodeine and codeine were consumed concomitantly, is reported. This case report may contribute to data on fatal blood concentrations of drugs with rare incidence. The relative retention times in capillary gas chromatography and full mass spectra of various opiates in their silylated forms, detected together in one sample, may serve as a helpful analytical reference for clinical and forensic toxicologists.

摘要

据报道,有一例致命的阿片类药物过量案例,患者同时服用了乙基吗啡、氢可酮、二氢可待因和可待因。该病例报告可能有助于补充罕见药物致死血药浓度的数据。在一个样本中同时检测到的各种阿片类药物硅烷化形式在毛细管气相色谱中的相对保留时间和全质谱,可为临床和法医毒理学家提供有用的分析参考。

相似文献

1
Fatal opiates overdose. Toxicological identification of various metabolites in a blood sample by GC-MS after silylation.致命阿片类药物过量。硅烷化后通过气相色谱-质谱联用仪对血样中各种代谢物进行毒理学鉴定。
Forensic Sci Int. 1998 Jun 22;94(3):201-9. doi: 10.1016/s0379-0738(98)00077-2.
2
Evaluation of a method for simultaneous quantification of codeine, ethylmorphine and morphine in blood.
Forensic Sci Int. 1991 Oct;51(1):105-10. doi: 10.1016/0379-0738(91)90210-a.
3
GC-MS quantitation of codeine, morphine, 6-acetylmorphine, hydrocodone, hydromorphone, oxycodone, and oxymorphone in blood.血液中可待因、吗啡、6-乙酰吗啡、氢可酮、氢吗啡酮、羟考酮和羟吗啡酮的气相色谱-质谱联用定量分析。
J Anal Toxicol. 2005 Jul-Aug;29(5):301-8. doi: 10.1093/jat/29.5.301.
4
Automated sample preparation by on-line dialysis and trace enrichment. Analysis of morphine, 6-monoacetylmorphine, codeine, ethylmorphine and pholcodine in plasma and whole blood by capillary gas chromatography and capillary gas chromatography-mass spectrometry.
J Chromatogr. 1993 Nov 17;621(1):41-8.
5
GCD quantitation of opiates as propionyl derivatives in blood.血液中作为丙酰衍生物的阿片类药物的气相色谱-质谱联用定量分析
J Anal Toxicol. 2000 Mar;24(2):122-6. doi: 10.1093/jat/24.2.122.
6
Application of the combined use of fused silica capillary columns and NPD for the toxicological determination of codeine and ethylmorphine in a human overdose case.熔融石英毛细管柱与氮磷检测器联用在一例人体过量服用案件中对可待因和乙基吗啡进行毒理学测定的应用。
J Anal Toxicol. 1983 May-Jun;7(3):113-5. doi: 10.1093/jat/7.3.113.
7
Toxicological detection of pholcodine in blood, urine and hair in three cases of fatal intoxication.三例致死性中毒中血液、尿液和头发中福可定的毒理学检测。
Forensic Sci Int. 2021 Oct;327:110975. doi: 10.1016/j.forsciint.2021.110975. Epub 2021 Aug 20.
8
Distinction among eight opiate drugs in urine by gas chromatography-mass spectrometry.气相色谱-质谱法鉴别尿液中的八种阿片类药物。
J Pharm Biomed Anal. 1999 Sep;20(5):815-28. doi: 10.1016/s0731-7085(99)00086-2.
9
The detection of dihydrocodeine and its main metabolites in cases of fatal overdose.
Int J Legal Med. 1999;112(3):155-8. doi: 10.1007/s004140050222.
10
Evaluation of urinary dihydrocodeine excretion in human by gas chromatography-mass spectrometry.气相色谱-质谱法对人体尿中双氢可待因排泄情况的评估。
J Chromatogr B Biomed Sci Appl. 2001 Mar 5;752(1):179-86. doi: 10.1016/s0378-4347(00)00509-0.