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特发性草酸钙肾结石病中高草酸尿症的患病率。

Prevalence of hyperoxaluria in idiopathic calcium oxalate kidney stone disease.

作者信息

Baggio B, Gambaro G, Favaro S, Borsatti A

出版信息

Nephron. 1983;35(1):11-4. doi: 10.1159/000183037.

DOI:10.1159/000183037
PMID:6888620
Abstract

Urinary excretion of oxalate, calcium and urate has been investigated in 88 patients affected by idiopathic calcium oxalate stone disease and in 20 normal subjects. Of these ions, only oxalate was found significantly higher in stone formers. Defining hyperoxaluria as urinary oxalate excretion greater than 2 SD above normal, 50% of stone-forming people were found to be hyperoxaluric. When stone formers were classified in normo- and hyperoxaluric, the prevalence of hypercalciuria, hyperuricuria, family history of stone disease and recurrencies in stone formation was the same in both groups. It is concluded that hyperoxaluria is a frequent finding in finding in idiopathic calcium oxalate renal stone disease.

摘要

对88例特发性草酸钙结石病患者及20名正常受试者的草酸、钙和尿酸的尿排泄情况进行了研究。在这些离子中,仅发现结石形成者的草酸水平显著更高。将高草酸尿症定义为尿草酸排泄量高于正常水平2个标准差以上,发现50%的结石形成者患有高草酸尿症。当将结石形成者分为正常草酸尿症组和高草酸尿症组时,两组的高钙尿症、高尿酸尿症、结石病家族史及结石复发率相同。结论是,高草酸尿症在特发性草酸钙肾结石病中很常见。

相似文献

1
Prevalence of hyperoxaluria in idiopathic calcium oxalate kidney stone disease.特发性草酸钙肾结石病中高草酸尿症的患病率。
Nephron. 1983;35(1):11-4. doi: 10.1159/000183037.
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[Comparative study of urinary calcium, oxalate and uric acid in calcium oxalate lithiasis].草酸钙结石患者尿钙、草酸和尿酸的对比研究
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Age, Body Mass Index, and Gender Predict 24-Hour Urine Parameters in Recurrent Idiopathic Calcium Oxalate Stone Formers.年龄、体重指数和性别可预测复发性特发性草酸钙结石形成者的24小时尿液参数。
J Endourol. 2017 Dec;31(12):1335-1341. doi: 10.1089/end.2017.0352.
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The variability and dietary dependence of urinary oxalate excretion in recurrent calcium stone formers.复发性草酸钙结石患者尿草酸排泄的变异性及饮食依赖性
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The urinary response to an oral oxalate load in recurrent calcium stone formers.复发性草酸钙结石患者口服草酸盐负荷后的尿液反应。
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[Studies of urinary risk factors in urolithiasis].[尿路结石的尿液危险因素研究]
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Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group.肾结石形成的尿液危险因素的饮食治疗。CLU工作组综述
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2
Sel1-like proteins and peptides are the major -derived factors stimulating oxalate transport by human intestinal epithelial cells.Sel1 样蛋白和肽是刺激人肠上皮细胞草酸转运的主要衍生因子。
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蛋白激酶 A 信号通路的激活可刺激人肠道 Caco2-BBE 细胞的草酸盐转运。
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The general practitioner and nephrolithiasis.全科医生与肾结石病
Clin Cases Miner Bone Metab. 2008 May;5(2):145-8.
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Evidence for net renal tubule oxalate secretion in patients with calcium kidney stones.证据表明,钙肾结石患者的肾单位肾小管存在净草酸分泌。
Am J Physiol Renal Physiol. 2011 Feb;300(2):F311-8. doi: 10.1152/ajprenal.00411.2010. Epub 2010 Dec 1.
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Pharmacology of stone disease.结石病药理学
Adv Chronic Kidney Dis. 2009 Jan;16(1):30-8. doi: 10.1053/j.ackd.2008.10.004.
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Recent advances in the pathophysiology of nephrolithiasis.肾结石病病理生理学的最新进展。
Kidney Int. 2009 Mar;75(6):585-95. doi: 10.1038/ki.2008.626. Epub 2008 Dec 10.