Kolesnik Iu M, Orestenko Iu N
Probl Endokrinol (Mosk). 1983 Jul-Aug;29(4):55-9.
In experiments on 17 Wistar rats the physiological activity was studied after stereotaxic electrode implantation according to the indices of the pulse rate and impedance, hypothalamic paraventricular nucleus and dorsal hippocamp under conditions of 30-day barochamber hypoxia (6 hours daily), at the imitated "height" of 6 km. The change recurrence was found, characterized by a prolonged period of the nucleus activation with parallel protective relieving inhibition of the dorsal hippocamp, followed by a fall in the nucleus activity and a marked hippocamp stimulation with hyporeactivity of the organism on hypoxia itself. The subsequent wave of the nucleus activation was transitory and was accompanied again by the hippocamp inhibition. The observed cyclic changes in physiological processes of the nucleus and hippocamp showed the mechanism of development of the organism adaptation to hypoxia.
在对17只Wistar大鼠进行的实验中，根据心率和阻抗指标，研究了在模拟6千米“高度”的30天气压舱缺氧（每天6小时）条件下，立体定向电极植入下丘脑室旁核和背侧海马后的生理活动。发现了变化的重复性，其特征是核激活期延长，同时背侧海马受到平行的保护性缓解抑制，随后核活动下降，机体对缺氧本身反应低下的情况下海马受到明显刺激。随后的核激活波是短暂的，并且再次伴随着海马抑制。观察到的核和海马生理过程中的周期性变化表明了机体适应缺氧的发展机制。
