肉芽肿性乳腺炎：7例报告

Fletcher A, Magrath I M, Riddell R H, Talbot I C

J Clin Pathol. 1982 Sep;35(9):941-5. doi: 10.1136/jcp.35.9.941.

The clinical history and histological features of seven cases of granulomatous mastitis are presented. The lesion occurs in young parous women as a tender extra-areolar breast lump. Histologically, non-caseating discrete granulomas are present, confined to breast lobules with, in three cases, coalescence of the granulomas and microabscess formation. Pathogenesis of the changes is discussed. It is thought that granulomatous mastitis is an entity morphologically distinct from duct ectasia/plasma cell mastitis and the commoner forms of granulomatous breast diseases.

本文介绍了7例肉芽肿性乳腺炎的临床病史和组织学特征。该病变发生于年轻经产妇，表现为乳晕外乳房压痛性肿块。组织学上，存在非干酪样散在肉芽肿，局限于乳腺小叶，3例出现肉芽肿融合及微脓肿形成。文中讨论了这些改变的发病机制。认为肉芽肿性乳腺炎在形态学上是一种与导管扩张/浆细胞性乳腺炎及常见的肉芽肿性乳腺疾病不同的实体。