Leeson T S
J Anat. 1982 Jun;134(Pt 4):653-66.
The terminal web-brush border complex of rodent duodenal enterocytes has been studied by electron microscopy to investigate its structure in relation to currently accepted models of motility in this region. The main adherens zone is composed chiefly of a fine feltwork of 5 to 7 nm filaments, some of which originate in zonulae adherentes. In some cells, this is not a complete layer or sheet. Passing into it from its deep aspect are 10 nm tonofilaments, which also form the basal zone. The filament density in the basal zone is less than that of the adherens zone, and many of the tonofilaments are associated with spot desmosomes. The apical zone contains a loose meshwork of 5 to 7 nm filaments with more filaments lying adjacent to plasmalemmae of the zonula occludens. The core of each microvillus contains a bundle of 17 to 48 microfilaments, 5-7 nm in diameter, apparently attached to the apical plasmalemma and with some slender cross filaments between core filaments and the plasmalemma. In the main, these core bundles of microfilaments pass deeply into and often through the adherens zone of the terminal web where they terminate abruptly. Filaments of the terminal web appear to interconnect microfilaments of adjacent core bundles but without positive evidence of 'splaying' of microfilaments of a core bundle within the adherens zone. These findings are discussed in relation to movement of microvilli.
利用电子显微镜对啮齿动物十二指肠肠上皮细胞的终末网 - 刷状缘复合体进行了研究，以探究其结构与该区域目前公认的运动模型之间的关系。主要的黏附带主要由5至7纳米细丝构成的精细网络组成，其中一些细丝起源于黏着小带。在一些细胞中，这不是一个完整的层或片层。从其深部进入的是10纳米的张力丝，它们也构成了基底部区域。基底部区域的细丝密度低于黏附带，并且许多张力丝与点状桥粒相关联。顶端区域包含5至7纳米细丝的疏松网络，更多的细丝位于紧密连接的质膜附近。每个微绒毛的核心包含一束17至48根微丝，直径为5 - 7纳米，显然附着于顶端质膜，并且在核心细丝和质膜之间有一些细长的交叉细丝。总体而言，这些微丝核心束深深进入并常常穿过终末网的黏附带，在那里它们突然终止。终末网的细丝似乎将相邻核心束的微丝相互连接，但没有确凿证据表明黏附带内核心束的微丝有“散开”现象。结合微绒毛的运动对这些发现进行了讨论。
