Binder E, Holopainen E, Malmberg H, Salo O
Allergy. 1982 Aug;37(6):389-96. doi: 10.1111/j.1398-9995.1982.tb02317.x.
In a study of 770 patients with allergic rhinitis, anamnestic data were collected by means of a questionnaire. 484 (63%) of the patients were women and 286 (37%) men. 45.5% of the patients had perennial symptoms, 33.5% had seasonal symptoms only, and 21% had predominantly seasonal but also some perennial symptoms. More than 50% of the patients belonged to the age group 21-40 years. The seasonal group included significantly more young patients than the perennial group. More than 50% of the parents and about 45% of the siblings had some atopic disorder. About 20% of the rhinitis patients had a concomitant allergic disorder. Sneezing was the commonest complaint in both rhinitis groups, but it was significantly more frequent in patients with seasonal rhinitis. Nasal blockage, again, was significantly commoner in perennial rhinitis. More than half of the patients reported severest symptoms in the morning. 282 patients had some domestic animal or pet, and 34% of these developed symptoms when close to an animal. Hypersensitivity to animals was significantly more frequent in patients who had domestic animals or pets than in those who did not. There was a clear correlation in perennial allergic rhinitis between the duration of rhinitis and deterioration of the sense of smell.
在一项针对770名变应性鼻炎患者的研究中,通过问卷调查收集既往病史数据。患者中484名(63%)为女性,286名(37%)为男性。45.5%的患者有常年性症状,33.5%的患者仅有季节性症状,21%的患者以季节性症状为主但也有一些常年性症状。超过50%的患者年龄在21至40岁之间。季节性变应性鼻炎组的年轻患者明显多于常年性变应性鼻炎组。超过50%的父母和约45%的兄弟姐妹有某种特应性疾病。约20%的鼻炎患者伴有变应性疾病。打喷嚏是两组鼻炎患者最常见的主诉,但在季节性鼻炎患者中更为频繁。鼻塞在常年性鼻炎中同样明显更为常见。超过一半的患者报告早晨症状最严重。282名患者饲养了某种家畜或宠物,其中34%在靠近动物时出现症状。饲养家畜或宠物的患者对动物过敏的情况明显多于未饲养者。在常年性变应性鼻炎中,鼻炎病程与嗅觉减退之间存在明显相关性。