Benson D F, Stuss D T
Neurology. 1982 Dec;32(12):1353-7. doi: 10.1212/wnl.32.12.1353.
The effect of bilateral frontal leukotomy on motor function was evaluated by neurologic examination, tests of praxis, and appropriate neuropsychologic tests administered to five groups of subjects. Postleukotomy schizophrenic patients were subdivided into three degrees of recovery. Two nonleukotomized groups served as controls for effects of schizophrenia, age, and education. The results indicate that the size of the bifrontal damage was not significant in the response to the motor tests, whereas the severity of schizophrenia clearly affected results. As tested, bilateral orbitofrontal white matter lesions did not disturb motor competency.
通过对五组受试者进行神经学检查、实践测试和适当的神经心理学测试,评估双侧额叶白质切断术对运动功能的影响。白质切断术后的精神分裂症患者被细分为三个恢复程度。两个未接受白质切断术的组作为精神分裂症、年龄和教育影响的对照组。结果表明,双侧额叶损伤的大小对运动测试的反应并不显著,而精神分裂症的严重程度明显影响测试结果。经测试,双侧眶额白质病变并未干扰运动能力。