Stuss D T, Benson D F, Kaplan E F, Della Malva C L, Weir W S
Bull Clin Neurosci. 1984;49:43-51.
Visuoperceptive and visuoconstructive tests were administered to three groups of schizophrenics who had undergone bilateral prefrontal leucotomy approximately 25 years earlier. A nonoperated schizophrenic patient group and a normal subject group served as controls for the effects of schizophrenic symptomatology and for age and education. The results demonstrated that orbital frontal white matter lesions do not disturb simple perceptions and constructions. The nonoperated schizophrenics had significant problems on many of the tests. Only one test, the WAIS Picture Arrangement, revealed deficits in all patient groups, including the good recovery leucotomized patients. This suggests impairment in the higher-order control and organization of perceptual material which may be secondary to orbital frontal white matter lesions or reflect aspects of the underlying schizophrenic disorder.
对三组大约在25年前接受过双侧前额叶白质切除术的精神分裂症患者进行了视觉感知和视觉构建测试。一组未接受手术的精神分裂症患者和一组正常受试者作为对照，以研究精神分裂症症状以及年龄和教育程度的影响。结果表明，眶额叶白质损伤不会干扰简单的感知和构建。未接受手术的精神分裂症患者在许多测试中都存在显著问题。只有一项测试，即韦氏成人智力量表图片排列测试，显示所有患者组（包括恢复良好的接受白质切除术的患者）均存在缺陷。这表明在感知材料的高阶控制和组织方面存在损伤，这可能继发于眶额叶白质损伤，或反映了潜在精神分裂症的某些方面。
