Jørgensen M, Mortensen J Z, Madsen A G, Thorsen S, Jacobsen B
Scand J Haematol. 1982 Sep;29(3):217-23. doi: 10.1111/j.1600-0609.1982.tb00586.x.
6 members of a family with a tendency to thrombosis and defective fibrinolysis were examined. After stimulation of plasminogen activator release from the vessel wall by local venous occlusion or by submaximal physical exercise, they had a lower plasminogen activator activity in blood than a healthy control group (P less than 0.01). 5 of the examined members suffered from recurrent venous thrombosis. The defect appeared to be autosomal dominant.
对一个有血栓形成倾向和纤维蛋白溶解缺陷的家族中的6名成员进行了检查。通过局部静脉阻塞或次最大量体育锻炼刺激血管壁释放纤溶酶原激活物后，他们血液中的纤溶酶原激活物活性低于健康对照组（P<0.01）。6名受检成员中有5人患有复发性静脉血栓形成。该缺陷似乎为常染色体显性遗传。
