Hågå P, Ek J, Kran S
Am J Clin Nutr. 1982 Dec;36(6):1200-4. doi: 10.1093/ajcn/36.6.1200.
Plasma tocopherol, beta-lipoprotein concentrations, and tocopherol/beta-lipoprotein ratios were studied during 40 normal pregnancies. The levels in 36 cord blood samples from the newborn of these pregnancies and in 25 normal nonpregnant women were also determined. In agreement with earlier studies plasma tocopherol levels rose gradually and significantly during pregnancy, while the levels in cord blood were much lower. Beta-lipoprotein concentrations showed similar changes as for tocopherol, rendering the tocopherol/beta-lipoprotein ration unchanged during gestation. The ratios in cord blood and in nonpregnant women were similar to those of pregnant women. A significant positive correlation (r=0.84, p less than 0.001) was found between tocopherol and beta-lipoprotein concentrations. The results indicate that the increased plasma tocopherol levels during pregnancy and the low levels in cord blood result from differences in plasma transport capacity.
在40例正常妊娠期间，对血浆生育酚、β-脂蛋白浓度以及生育酚/β-脂蛋白比率进行了研究。还测定了这些妊娠新生儿的36份脐血样本以及25名正常未孕女性的上述指标。与早期研究一致，妊娠期间血浆生育酚水平逐渐显著升高，而脐血中的水平则低得多。β-脂蛋白浓度与生育酚呈现相似变化，使得生育酚/β-脂蛋白比率在妊娠期保持不变。脐血和未孕女性中的比率与孕妇相似。生育酚与β-脂蛋白浓度之间存在显著正相关（r = 0.84，p < 0.001）。结果表明，妊娠期间血浆生育酚水平升高以及脐血中水平较低是由于血浆运输能力的差异所致。
