Yogev L, Terkel J
J Endocrinol. 1982 Dec;95(3):397-402. doi: 10.1677/joe.0.0950397.
During pseudopregnancy in the rat prolactin is secreted autonomously in a characteristic pattern of two daily surges, one nocturnal and one diurnal. The present study investigated whether, during lactation, prolactin secretion occurred in an autonomous nightly surge pattern, in addition to secretion resulting from suckling stimulation. Nocturnal levels of prolactin were measured daily for 2 weeks in lactating rats which were separated from their young from 21.00 to 06.00 h. It was found that no nocturnal prolactin surges were present throughout the 2 weeks of lactation. In addition, it was observed that after pups were removed for 3 h prolactin levels were lower during the first week of lactation than during the second week. It was concluded that lactational dioestrus is distinguished from pseudopregnancy by the absence of autonomous secretion of prolactin in the pattern of a nocturnal surge.
在大鼠假孕期间，催乳素以每天两次分泌高峰的特征模式自主分泌，一次在夜间，一次在白天。本研究调查了在哺乳期，除了因哺乳刺激而分泌外，催乳素分泌是否以自主的夜间高峰模式发生。在从21:00至06:00与幼崽分开的哺乳期大鼠中，每天测量夜间催乳素水平，持续2周。结果发现，在整个2周的哺乳期内均未出现夜间催乳素高峰。此外，观察到在幼崽被拿走3小时后，哺乳期第一周的催乳素水平低于第二周。得出的结论是，哺乳期的间情期与假孕的区别在于不存在催乳素以夜间高峰模式的自主分泌。
