Nikolai T F, Brosseau J, Kettrick M A, Roberts R, Beltaos E
Arch Intern Med. 1980 Apr;140(4):478-82.
Spontaneously resolving hyperthyroidism (SRH) is a transient form of hyperthyroidism characterized by a painless, nontender, normal-sized or slightly enlarged thyroid gland, elevated levels of thyroxine and triiodothyronine, a depressed thyroid radioactive iodine uptake (RAIU), spontaneous resolution in two to five months, and a focal or diffuse lymphocytic thyroiditis on biopsy. Since 1962, 62 episodes of SRH were found in 56 individuals. Twelve thyroid biopsy specimens showed diffuse or focal lymphocytic thyroiditis. Testing of viral antibodies to a wide range of viruses demonstrated only one patient with notable titer change of 18 tested. Resolution of the hyperthyroidism took two to five months. Four patients were treated inappropriately. Lymphocytic thyroiditis with spontaneously resolving hyperthyroidism appears to be a new syndrome that has dramatically increased in frequency in the past ten years. It is difficult to differentiate from common forms of hyperthyroidism unless RAIU is determined.
自发性缓解型甲状腺功能亢进症（SRH）是一种短暂性甲状腺功能亢进症，其特征为甲状腺无痛、无压痛、大小正常或略肿大，甲状腺素和三碘甲状腺原氨酸水平升高，甲状腺放射性碘摄取（RAIU）降低，在两到五个月内自发缓解，活检显示为局灶性或弥漫性淋巴细胞性甲状腺炎。自1962年以来，在56名个体中发现了62例SRH发作。12份甲状腺活检标本显示为弥漫性或局灶性淋巴细胞性甲状腺炎。对多种病毒的病毒抗体检测显示，在18名接受检测的患者中只有1例抗体滴度有显著变化。甲状腺功能亢进症的缓解持续了两到五个月。4名患者接受了不恰当的治疗。淋巴细胞性甲状腺炎伴自发性缓解型甲状腺功能亢进症似乎是一种新综合征，在过去十年中发病率显著增加。除非测定RAIU，否则很难与常见类型的甲状腺功能亢进症相鉴别。
