Glasser C M, Bhagavan B S
Arch Pathol Lab Med. 1980 May;104(5):272-5.
Forty-six carcinoid tumors of the appendix, diagnosed in surgically resected specimens during an 11-year period (1965 to 1975) were reviewed to determine the features of metastasizing tumors. Of the carcinoid tumors of the appendix, 8.8% were found to metastasize to regional lymph nodes. The most reliable criterion of metastasizing tumors was the size of the primary tumor. Such tumors measured 2.0 cm or larger in greatest dimensions. Depth of invasion, extension to serosa, perineural involvement, histologic features, and location of the tumor relative to the length of the appendix were common to both the metastasizing and localized tumors. The surgical management of patients with carcinoid tumors of the appendix is controversial, ranging from a simple appendectomy to a more radical operative procedure. In the absence of distant metastases, it would appear that this group of patients with tumors 2.0 cm or more would require a right hemicolectomy rather than a simple appendectomy to accomplish removal of all disease-bearing tissue.
回顾了1965年至1975年这11年间在手术切除标本中诊断出的46例阑尾类癌肿瘤，以确定转移性肿瘤的特征。在阑尾类癌肿瘤中，发现8.8%会转移至区域淋巴结。转移性肿瘤最可靠的标准是原发肿瘤的大小。此类肿瘤最大直径测量为2.0厘米或更大。转移性肿瘤和局限性肿瘤在浸润深度、浆膜侵犯、神经周围受累、组织学特征以及肿瘤相对于阑尾长度的位置方面都很常见。阑尾类癌肿瘤患者的手术治疗存在争议，从简单的阑尾切除术到更激进的手术程序不等。在没有远处转移的情况下，似乎这群肿瘤直径为2.0厘米或更大的患者需要进行右半结肠切除术，而不是简单的阑尾切除术，以彻底切除所有病变组织。
