Incorporation of dipalmitoyl phosphatidycholine into human plasma low density lipoproteins: effects on composition and structure.

Bovine liver phosphatidylcholine exchange protein was used to transfer di[14C]palmitoyl phosphatidylcholine from sonicated vesicles to human plasma low density lipoproteins (LDL). The incorporation of di[14C]-palmitoyl phosphatidylcholine into LDL was associated with an increased percentage of total phospholipid and increased lipid rigidity as shown by an increase in the fluorescence polarization of 12-(9-anthroyloxy)-stearic acid and 1,6-diphenyl-1,3,5-hexatriene.