四膜虫对6-甲基嘌呤和放线菌酮的诱导抗性。II. 嗜热栖热四膜虫微核营养培养物和梨形四膜虫无核营养培养物中的变异
Induced resistance to 6-methylpurine and cycloheximide in Tetrahymena. II. Variation within vegetative cultures of micronucleate T. thermophila and amicronucleate T. pyriformis.
作者信息
Byrne B C
出版信息
Genetics. 1978 Aug;89(4):703-10. doi: 10.1093/genetics/89.4.703.
Abstract
Resistance to 6-methylpurine and cycloheximide has been induced in both the micronucleate species Tetrahymena thermophila and the amicronucleate species T. pyriformis. Resistance follows only after mutagen treatment and vegetative growth. The frequencies with which resistant variants are induced and the independence of mutagenesis and selection are demonstrated. All evidence is consistent with the hypothesis that macronuclear subunits are assorting in both species during vegetative growth to produce new phenotypes among subclones.
摘要
在微核物种嗜热四膜虫和无核物种梨形四膜虫中均已诱导出对6-甲基嘌呤和环己酰亚胺的抗性。抗性仅在诱变处理和营养生长后出现。证明了诱导抗性变体的频率以及诱变和选择的独立性。所有证据都与以下假设一致：在营养生长期间，两个物种的大核亚基都在进行分类，以在亚克隆中产生新的表型。
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