Dubin B, MacLennan W J, Hamilton J C
Gerontology. 1978;24(6):473-6. doi: 10.1159/000212287.
Tetracosactrin (Synacthen) tests were performed on 19 elderly women who had leucocyte ascorbic acid (LAA) levels of less than 15 microgram/108 WBC. 9 were then given a daily dose of 200 mg ascorbic acid orally for 2 weeks while the other 10 were left untreated. Following this, tetracosactrin tests were repeated in both groups. All initial plasm cortisol responses to tetracosactrin were within normal limits. Treatment with ascorbic acid produced no changes in these. This suggests that the low LAA levels often found in old people do not result in adrenal insufficiency.
对19名白细胞抗坏血酸（LAA）水平低于15微克/1.08×10⁸白细胞的老年女性进行了二十四肽促皮质素（辛纳科特）试验。然后，9名女性每天口服200毫克抗坏血酸，持续2周，而另外10名女性未接受治疗。在此之后，两组都重复进行了二十四肽促皮质素试验。所有最初对二十四肽促皮质素的血浆皮质醇反应均在正常范围内。抗坏血酸治疗后这些反应没有变化。这表明老年人中常见的低LAA水平不会导致肾上腺功能不全。
