动脉平滑肌中的肌球蛋白磷酸化与横桥循环
Myosin phosphorylation and the cross-bridge cycle in arterial smooth muscle.
作者信息
Dillon P F, Aksoy M O, Driska S P, Murphy R A
出版信息
Science. 1981 Jan 30;211(4481):495-7. doi: 10.1126/science.6893872.
PMID:6893872
Abstract
Phosphorylation of the 20,000-dalton light chain of myosin is closely correlated with cross-bridge cycling in arterial smooth muscle. Evidence is presented that dephosphorylation can produce an attached, noncycling cross-bridge (latch-bridge) which is responsible for the high economy of force maintenance in this tissue.
摘要
肌球蛋白20,000道尔顿轻链的磷酸化与动脉平滑肌中的横桥循环密切相关。有证据表明，去磷酸化可产生一种附着的、非循环的横桥（闩锁桥），它负责该组织中维持力量的高经济性。
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