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动脉平滑肌中的肌球蛋白磷酸化与横桥循环

Myosin phosphorylation and the cross-bridge cycle in arterial smooth muscle.

作者信息

Dillon P F, Aksoy M O, Driska S P, Murphy R A

出版信息

Science. 1981 Jan 30;211(4481):495-7. doi: 10.1126/science.6893872.

DOI:10.1126/science.6893872
PMID:6893872
Abstract

Phosphorylation of the 20,000-dalton light chain of myosin is closely correlated with cross-bridge cycling in arterial smooth muscle. Evidence is presented that dephosphorylation can produce an attached, noncycling cross-bridge (latch-bridge) which is responsible for the high economy of force maintenance in this tissue.

摘要

肌球蛋白20,000道尔顿轻链的磷酸化与动脉平滑肌中的横桥循环密切相关。有证据表明,去磷酸化可产生一种附着的、非循环的横桥(闩锁桥),它负责该组织中维持力量的高经济性。

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