Iashchenko L V
Biull Eksp Biol Med. 1980 Dec;90(12):668-8.
A foreign body was introduced into the rabbit abdominal cavity. Macrophages, polymorphonuclear leukocytes (PMNL), lymphocytes of the abdomino-cavitary exudate, blood, trachea were examined cytochemically, whilst the tissue being formed around the foreign body and lungs were subjected to histological study. It was shown that three levels of structural and functional reconstitution of macrophages, PMNL and lymphocytes accompanied the development of aseptic inflammation. The system level determines the likeness of alterations of macrophages, PMNL and lymphocytes of different sites. The regional and cellular levels are responsible for the difference between the cells of different sites and types. A relationship was disclosed between the system reconstitution and the local (capsule) and distant (lung) tissue inflammation. The alterative and exudative tissue processes depend on the damage to macrophages, PMNL and lymphocytes. Meanwhile the proliferative processes depend on the changes in the biosynthesis of these cells.
将异物植入兔腹腔。对腹腔渗出液、血液、气管中的巨噬细胞、多形核白细胞(PMNL)、淋巴细胞进行了细胞化学检查,同时对异物周围形成的组织和肺进行了组织学研究。结果表明,无菌性炎症的发展伴随着巨噬细胞、PMNL和淋巴细胞结构和功能重构的三个水平。系统水平决定了不同部位巨噬细胞、PMNL和淋巴细胞变化的相似性。区域和细胞水平则决定了不同部位和类型细胞之间的差异。揭示了系统重构与局部(包膜)和远处(肺)组织炎症之间的关系。变性和渗出性组织过程取决于巨噬细胞、PMNL和淋巴细胞的损伤。同时,增殖过程取决于这些细胞生物合成的变化。