Birkun A A, Iashchenko L V
Biull Eksp Biol Med. 1978;86(7):104-7.
The authors present the results of a comparative cytochemical study of the phagocytes' and lymphocytes' lysosomal membranes state in the rabbit blood, trachea and lungs in immunization with sorbed staphylococcus toxoid and human serum albumin in experimental pneumonia and in this disease against the background of immunization. It was shown that the changes resulting from immunization (the phagocytes' and lymphocytes' lysosomal membranes systemic destabilization, microcirculatory disorders, and cell infiltration in the lungs) were premorbid to pneumonia and intensified the inflammation. The authors considered these changes to be structural and functional signs of the immunopathological reactions accompanying pneumonia.
作者展示了一项比较细胞化学研究的结果，该研究针对兔血液、气管和肺部中吞噬细胞与淋巴细胞的溶酶体膜状态，研究内容为在实验性肺炎中以及在免疫背景下的该疾病中，用吸附类葡萄球菌类毒素和人血清白蛋白进行免疫的情况。结果表明，免疫所导致的变化（吞噬细胞与淋巴细胞的溶酶体膜系统性不稳定、微循环紊乱以及肺部细胞浸润）在肺炎发病前就已出现，并加剧了炎症。作者认为这些变化是伴随肺炎的免疫病理反应的结构和功能特征。
