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合成磷脂预转变的动力学。一项量热学研究。

Kinetics of the pretransition of synthetic phospholipids. A calorimetric study.

作者信息

Cho K C, Choy C L, Young K

出版信息

Biochim Biophys Acta. 1981 Jan 26;663(1):14-21. doi: 10.1016/0005-2760(81)90190-9.

DOI:10.1016/0005-2760(81)90190-9
PMID:6894249
Abstract

The pretransition in aqueous dispersions of two synthetic phospholipids (dimyristoylphosphatidylcholine and dipalmitoylphosphatidylcholine) has been examined in detail by differential scanning calorimetry. The transition from the high-temperature state (state above pretransition) to the low-temperature state (state below pretransition) is complex and appears to occur via some metastable states. In contrast, the kinetics of the transition from the low- to the high-temperature state is consistent with an activated two-state model. The observed hysteresis is shown to arise mainly from the kinetic nature of the pretransition.

摘要

通过差示扫描量热法详细研究了两种合成磷脂(二肉豆蔻酰磷脂酰胆碱和二棕榈酰磷脂酰胆碱)水分散体中的预转变。从高温状态(预转变以上的状态)到低温状态(预转变以下的状态)的转变很复杂,似乎是通过一些亚稳态发生的。相比之下,从低温状态到高温状态的转变动力学与活化二态模型一致。观察到的滞后现象主要源于预转变的动力学性质。

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引用本文的文献

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2
Metastability and polymorphism in the gel phase of 1,2-dipalmitoyl-3-SN-phosphatidylcholine. A Fourier transform infrared study of the subtransition.1,2-二棕榈酰-3-SN-磷脂酰胆碱凝胶相中的亚稳性和多态性。亚转变的傅里叶变换红外光谱研究。
Biophys J. 1982 May;38(2):175-84. doi: 10.1016/S0006-3495(82)84544-X.
3
Kinetics of the premelting (L beta'-P beta') and main transition (P beta'-L alpha) in hydrated dipalmitoylphosphatidylcholine. A time-resolved x-ray diffraction study using microwave-induced temperature-jumps.
水合二棕榈酰磷脂酰胆碱中预熔解(Lβ'-Pβ')和主要转变(Pβ'-Lα)的动力学。一项使用微波诱导温度跳跃的时间分辨X射线衍射研究。
Biophys J. 1990 Sep;58(3):677-86. doi: 10.1016/S0006-3495(90)82410-3.