Kennerdell J S, Rosenbaum A E, El-Hoshy M H
Arch Ophthalmol. 1981 May;99(5):807-9. doi: 10.1001/archopht.1981.03930010807002.
Computed assisted tomography (CT) of seven cases of dysthyroid optic neuropathy showed moderate to severe thickening of the extraocular muscles at the orbital apex, white CT of two control cases of dysthyroid orbitopathy without neuropathy showed minimal or fusiform thickening. The consequences include probable apical compression with optic nerve neuropathy either by direct pressure on the nerve or its blood supply. The management of these cases is either by oral administration of corticosteroids in high dosage with gradual tapering or radiation therapy to the orbital apex (approximately 3,000 rad over a ten-day period). If surgical decompression is to be attempted, it should be designed to decompress the optic nerve at the orbital apex.
计算机辅助断层扫描（CT）显示，7例甲状腺功能异常性视神经病变患者眶尖处眼外肌呈中度至重度增厚，2例无神经病变的甲状腺功能异常性眼眶病对照病例的CT图像显示眼外肌仅有轻微增厚或呈梭形增厚。其后果可能是眶尖对视神经的压迫，无论是直接压迫神经还是其血供。这些病例的治疗方法要么是口服高剂量皮质类固醇并逐渐减量，要么是对眶尖进行放射治疗（10天内约3000拉德）。如果要尝试手术减压，应设计为对眶尖处的视神经进行减压。
