Jobe A, Ikegami M, Jacobs H
Biochim Biophys Acta. 1981 Apr 23;664(1):182-7. doi: 10.1016/0005-2760(81)90040-0.
Newborn rabbits delivered spontaneously at term and cared for by the mothers were studied from 0.5 to 12.5 days of age. Curves are constructed to describe the changes in weight, lung and alveolar wash phosphatidylcholine and saturated phosphatidylcholine, and lung protein. The curves are complex and non-linear. However. expressing the increases in lung and alveolar wash phosphatidylcholine and saturated phosphatidylcholine pool sizes relative to animals weight results in a decreasing linear relationship from 0.5 to 12.5 days of age. By 12.5 days the ratios of lung phosphatidylcholine and saturated phosphatidylcholine to weight approximate the ratios measured for adult rabbits. The ratios of saturated to total phosphatidylcholine in the alveolar washes and lungs remained invarient throughout the study period.
对足月自然分娩并由母兔照料的新生兔进行了研究，研究期为0.5至12.5日龄。构建了曲线来描述体重、肺和肺泡灌洗中的磷脂酰胆碱和饱和磷脂酰胆碱以及肺蛋白的变化。这些曲线复杂且呈非线性。然而，将肺和肺泡灌洗中磷脂酰胆碱和饱和磷脂酰胆碱池大小的增加相对于动物体重来表示时，在0.5至12.5日龄期间会呈现出递减的线性关系。到12.5日龄时，肺磷脂酰胆碱和饱和磷脂酰胆碱与体重的比值接近成年兔的测量比值。在整个研究期间，肺泡灌洗和肺中饱和磷脂酰胆碱与总磷脂酰胆碱的比值保持不变。
