Latapie J L, Lefort G, Commenges M, Roger P, Riviere L J, Mauriac L
Ann Endocrinol (Paris). 1980 Nov-Dec;41(6):601-5.
In graves' disease small amounts of radioactive iodine administered repeatedly on a monthly basis depending on the progress of the disease is a method whose effectiveness we have studied on 192 cases over a period of 3 to 7 years. Relapses (4 %), failures (11 %) permanent hypothyroidism (24 % after 7 years) and the duration of the active stage have been collated with different clinical or biological parameters in order better to define the main factors that determine the course and prognosis. The size of the goitre and the presence of antithyroglobulin antibodies are among the most significant.
在格雷夫斯病中，根据病情进展每月重复给予少量放射性碘，我们已对192例患者进行了3至7年的研究，以观察该方法的有效性。已将复发率（4%）、失败率（11%）、永久性甲状腺功能减退（7年后为24%）以及活跃期的持续时间与不同的临床或生物学参数进行了整理，以便更好地确定决定病程和预后的主要因素。甲状腺肿的大小和抗甲状腺球蛋白抗体的存在是其中最重要的因素。
