Mohn J F, Witebsky E
Haematologia (Budap). 1980;13(1-4):49-58.
Rabbits were selected on the basis of distinctly higher titers of preexisting heteroagglutinins in their normal sera for human group A1 and A2 erythrocytes than for group B and especially group O. They were injected intravenously with increasing volumes of either of two pools of human group A1 secretor saliva. Comparative titrations between the reimmunization and the 7--14-day postimmune sera clearly demonstrated that all the rabbits responded with increases in the titers of the agglutinins directed against human group A1 and group A2 red blood cells that averaged approximately 250-fold; whereas, the titers of those active against the group B cells increased but 9.2 times and of those reacting with the group O cells only by an average of 2.8 times.
之所以选择兔子，是基于其正常血清中针对人类A1和A2血型红细胞的预先存在的异种凝集素效价明显高于针对B型尤其是O型的效价。给它们静脉注射递增剂量的两批人类A1分泌型唾液中的任意一批。再次免疫血清与免疫后7 - 14天血清之间的比较滴定清楚地表明，所有兔子针对人类A1和A2红细胞的凝集素效价均有所增加，平均增加约250倍；而针对B型细胞的凝集素效价仅增加9.2倍，与O型细胞反应的凝集素效价平均仅增加2.8倍。
