大鼠肝微粒体对八氯噻平 - N - 氧化物的还原作用。 - Suppr

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Reduction of octoclothepine-N-oxide by rat liver microsomes.

作者信息

Helia O, Vargova E, Jindra A

出版信息

Eur J Drug Metab Pharmacokinet. 1981;6(2):155-8. doi: 10.1007/BF03189483.

DOI:10.1007/BF03189483

PMID:6895067

Abstract

摘要

相似文献

Reduction of octoclothepine-N-oxide by rat liver microsomes.大鼠肝微粒体对八氯噻平 - N - 氧化物的还原作用。

Eur J Drug Metab Pharmacokinet. 1981;6(2):155-8. doi: 10.1007/BF03189483.

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本文引用的文献

Meabolites of octoclothepin eliminated in human and ratuine.八氯噻平在人和大鼠体内的代谢产物。（注：原文中“ratuine”可能有误，推测应为“rat”即“大鼠” ）

Biochem J. 1969 Sep;114(2):339-42. doi: 10.1042/bj1140339.

Contribution to biotransformation of thiepin derivatives (octoclothepin and perathiepin) in vivo.

Act Nerv Super (Praha). 1968 Oct 3;10(3):335-6.

Comparative study on the pharmacological properties of the neuroleptics octoclothepine and chlorpromazine.

Act Nerv Super (Praha). 1967 Nov;9(4):424-5.

The pharmacology and biochemistry of N-oxides.N-氧化物的药理学与生物化学

Pharmacol Rev. 1969 Dec;21(4):325-55.

Evidence for the involvement of cytochrome P-450 in tiaramide N-oxide reduction.

Life Sci. 1974 Oct 15;15(8):1433-42. doi: 10.1016/0024-3205(74)90118-0.

Kinetic parameters of drug-metabolizing enzymes in Ca 2+ -sedimented microsomes from rat liver.

Biochem Pharmacol. 1972 Dec 15;21(24):3249-56. doi: 10.1016/0006-2952(72)90089-5.

[Oxidative biotransformation of clotepins (octoclothepin) in liver microsomes].

Pharmazie. 1979 Dec;34(12):852.

[Bile metabolites of octoclothepine in phenobarbital treated rats].

Pharmazie. 1978 Aug;33(8):539-40.

Reduction of tertiary amine N-oxide by purified cytochrome P-450.

Biochem Biophys Res Commun. 1977 Aug 22;77(4):1143-9. doi: 10.1016/s0006-291x(77)80098-3.

Reduction of tertiary amine N-oxides by liver microsomal cytochrome P-450.肝脏微粒体细胞色素P-450对叔胺N-氧化物的还原作用。

Mol Pharmacol. 1976 Mar;12(2):322-34.

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