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山羊胃肠道线虫抗驱虫药耐药性的调查

Investigations for anthelmintic resistance in gastrointestinal nematodes from goats.

作者信息

Hall C A, Ritchie L, McDonell P A

出版信息

Res Vet Sci. 1981 Jul;31(1):116-9.

PMID:6895558
Abstract

Field results from a commercial goat herd, based on egg counts and larval differentiation, suggested that anthelmintic resistance was present to albendazole, fenbendazole, levamisole, morantel, naphthalophos and phenothiazine. When the isolate was tested in sheep, using levamisole or oxfendazole, a possible resistance was shown for Trichostrongylus sp but no resistance was demonstrated in Haemonchus or Ostertagia spp. Ivermectin at a dose rate of 100 micrograms/kg was more than 98 per cent efficient in removing the adults of each of the three species of nematode. The phenomenon relating to the influence of the host on anthelmintic resistance is discussed.

摘要

一个商业山羊群的现场结果,基于虫卵计数和幼虫鉴别,表明对阿苯达唑、芬苯达唑、左旋咪唑、噻嘧啶、萘肽磷和吩噻嗪存在抗蠕虫药耐药性。当该分离株在绵羊中使用左旋咪唑或奥芬达唑进行测试时,显示对毛圆线虫属可能存在耐药性,但在血矛线虫属或奥斯特他线虫属中未证实有耐药性。剂量率为100微克/千克的伊维菌素在清除三种线虫成虫方面的效率超过98%。讨论了宿主对驱虫药耐药性影响的相关现象。

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