一群奶山羊中苯并咪唑类和非苯并咪唑类药物的现场评估。

A field evaluation of benzimidazole and nonbenzimidazole drugs in a herd of dairy goats.

作者信息

Uhlinger C, Fetrow J, Johnstone C

机构信息

Department of Food Animal and Equine Medicine, North Carolina State University, School of Veterinary Medicine, Raleigh 27606.

出版信息

J Vet Intern Med. 1988 Jul-Sep;2(3):113-6. doi: 10.1111/j.1939-1676.1988.tb02805.x.

DOI:10.1111/j.1939-1676.1988.tb02805.x

PMID:3225804

Abstract

A study was conducted to investigate the efficacy of six anthelmintics in a herd of dairy goats. Pretreatment larval cultures indicated that the goats were infected with Haemonchus contortus and Trichostrongylus colubriformis. Three separate treatment regimens were administered. In each trial, mature nonlactating goats were allocated into two treatment groups and a control group. Treatment groups received thiabendazole (TBZ) or levamisole (LEV), mebendazole (MBZ) or fenbendazole (FBZ), and morantel tartrate (MOR) or ivermectin (IVR). LEV, MOR, and IVR reduced fecal strongyle egg counts by 99% to 100% of pretreatment values. The benzimidazole (BZD) drugs changed pretreatment fecal egg counts by +2% to -32%. Results of posttreatment larval culture demonstrated the presence of H contortus larvae following the administration of BZD drugs.

摘要

进行了一项研究，以调查六种驱虫药对一群奶山羊的疗效。预处理幼虫培养表明，这些山羊感染了捻转血矛线虫和蛇形毛圆线虫。采用了三种不同的治疗方案。在每项试验中，将成熟的非泌乳山羊分为两个治疗组和一个对照组。治疗组分别接受噻苯达唑（TBZ）或左旋咪唑（LEV）、甲苯咪唑（MBZ）或芬苯达唑（FBZ）、以及酒石酸噻嘧啶（MOR）或伊维菌素（IVR）。LEV、MOR和IVR使粪便中圆线虫卵计数降低至预处理值的99%至100%。苯并咪唑（BZD）类药物使预处理后的粪便卵计数变化了+2%至-32%。治疗后幼虫培养结果表明，在施用BZD类药物后仍存在捻转血矛线虫幼虫。