The effects of azathioprine, clofibrate and tribenoside on leucocyte migration inhibition induced by vascular antigens in vascular disease.

The in vitro effects of azathioprine, clofibrate and tribenoside on the cell-mediated immune response was studied in some vascular diseases. Imuran decreased leucocyte migration inhibition induced by vascular antigens in patients with myocardial infarction, peripheral arterial disease or superficial thrombophlebitis. Clofibrate also moderated the cellular immune response in patients with myocardial infarction or peripheral arterial illness. Glyvenol did not show similar effects on leucocyte migration inhibition in patients with thrombophlebitis.