Horváth M, Szondy E, Ladányi A
Clin Exp Immunol. 1980 Sep;41(3):521-6.
The effect of autologous serum, Oradexon and heparin on the leucocyte migration inhibition induced by human vascular extracts was studied in patients with myocardial infarction, peripheral arterial disease and superficial thrombophlebitis. Comparing the effects of autologous serum and these drugs it was established that the reduction of migration inhibition with autologous serum was the lowest in all patients. The effect of Oradexon added to vascular extracts was similar in patients with myocardial infarction and thrombophlebitis. The migration inhibition caused by aorta extract was reduced by heparin in patients with myocardial infarction or obliterating arteriosclerosis, while in patients with thrombophlebitis treated with heparin there was no effect on the inhibition of leucocyte migration caused by vena extract.
在心肌梗死、外周动脉疾病和浅静脉炎患者中,研究了自体血清、奥沙拉秦(Oradexon)和肝素对人血管提取物诱导的白细胞迁移抑制的影响。比较自体血清和这些药物的作用后发现,在所有患者中,自体血清对迁移抑制的降低作用最小。在心肌梗死和静脉炎患者中,添加到血管提取物中的奥沙拉秦的作用相似。在心肌梗死或闭塞性动脉硬化患者中,肝素可降低主动脉提取物引起的迁移抑制,而在接受肝素治疗的静脉炎患者中,肝素对静脉提取物引起的白细胞迁移抑制没有影响。