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人精液中前列腺素的来源。

Origin of prostaglandins in human semen.

作者信息

Gerozissis K, Jouannet P, Soufir J C, Dray F

出版信息

J Reprod Fertil. 1982 Jul;65(2):401-4. doi: 10.1530/jrf.0.0650401.

DOI:10.1530/jrf.0.0650401
PMID:6896529
Abstract

The prostaglandins, PGE-1, PGE-2, PGF-1 alpha, PGF-2 alpha, 19-OH-PGE-(1 + 2), 19-OH-PGF-alpha were estimated by RIA in the semen of (a) normal men of proven fertility (total semen or split ejaculate); (b) men 1 year after vasectomy; and (c) men with agenesia of the vas deferens and seminal vesicles. PG concentrations in the semen of vasectomized men were largely within the normal ranges. In men with agenesia of the vas deferens and seminal vesicles, PG concentrations were 10(2) - 10(5)-fold less than that measured in normal subjects. The patterns of 19-OH-PGs and PGF-alpha in the five fractions of a split ejaculate followed in general the fructose profile. These data suggest that prostaglandins mostly originate in the seminal vesicles.

摘要

采用放射免疫分析法(RIA)对以下人群精液中的前列腺素PGE-1、PGE-2、PGF-1α、PGF-2α、19-OH-PGE-(1 + 2)、19-OH-PGF-α进行了测定:(a)经证实具有生育能力的正常男性(全精液或分段射精);(b)输精管结扎术后1年的男性;(c)输精管和精囊发育不全的男性。输精管结扎术后男性精液中的PG浓度大多在正常范围内。在输精管和精囊发育不全的男性中,PG浓度比正常受试者低10² - 10⁵倍。分段射精的五个部分中19-OH-PGs和PGF-α的模式总体上与果糖分布情况一致。这些数据表明,前列腺素大多起源于精囊。

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