Golden J W, Riddle D L
Science. 1982 Nov 5;218(4572):578-80. doi: 10.1126/science.6896933.
A Caenorhabditis-specific pheromone and the food supply influence both entry into and exit from a developmentally arrested juvenile stage called the dauer larva. The pheromone increases the frequency of dauer larva formation and inhibits recovery but does not affect adult behavior such as chemotaxis and egg laying. The fatty acid--like pheromone has been partially purified and characterized by a new bioassay. If similar developmental control mechanisms are used by parasitic nematodes, such mechanisms might be exploited to develop highly selective anthelmintic agents.
一种秀丽隐杆线虫特有的信息素和食物供应会影响进入和离开一个被称为滞育幼虫的发育停滞的幼年阶段。这种信息素会增加滞育幼虫形成的频率并抑制恢复，但不影响诸如趋化性和产卵等成虫行为。这种脂肪酸样信息素已通过一种新的生物测定法得到部分纯化和表征。如果寄生线虫使用类似的发育控制机制，那么这些机制可能会被用于开发高度选择性的驱虫剂。
