[Glauplex 2与硝酸毛果芸香碱对α-糜蛋白酶诱导的实验性青光眼的抗青光眼活性比较研究]
[Comparative study of the antiglaucomatous activity of Glauplex 2 and pilocarpine nitrate on alpha-chymotrypsin-induced experimental glaucoma].
作者信息
Andermann G, de Burlet G, Cannet C
出版信息
J Fr Ophtalmol. 1982;5(8-9):499-504.
PMID:6897256
Abstract
The antiglaucomatous effects of Glauplex 2 and pilocarpine nitrate on alpha-chymotrypsine-induced experimental glaucoma were studied in 8 rabbits. Changes in intraocular pressure were measured over a period of 12 hours after a single instillation of Glauplex 2 or two instillations of 2.6 p. cent pilocarpine nitrate at t = 0 and t = 6 hours. The antihypertensive effect of a single instillation of Glauplex 2 was shown to be approximately equivalent to that of two instillations of 2.6 p. cent pilocarpine nitrate.
摘要
在8只兔子身上研究了Glauplex 2和硝酸毛果芸香碱对α-糜蛋白酶诱导的实验性青光眼的抗青光眼作用。在t = 0和t = 6小时单次滴注Glauplex 2或两次滴注2.6%硝酸毛果芸香碱后，在12小时内测量眼压变化。结果显示，单次滴注Glauplex 2的降压效果与两次滴注2.6%硝酸毛果芸香碱的降压效果大致相当。
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