Delaquerriere-Richardson L, Anderson C, Jorch U M, Cook M
Vet Hum Toxicol. 1982 Dec;24(6):401-5.
This experiment studies the effects of low-level oral lead administration on bone in standardized colony-raised research male Beagles. Lead was administered to lactating mothers from parturition through weaning and directly to the pups thereafter. Results of bone radiographic morphometric and bone radiographic densitometric findings in five experimental and four control animals are reported. Total femoral length, and femoral diaphysal width, combined with cortical thickness, thickness/width ratio, and radiographic photodensitometry did not vary significantly between both groups, although bone lead and blood lead levels were significantly higher in the experimental group.
本实验研究了低剂量口服铅对标准化饲养的实验用雄性比格犬骨骼的影响。从分娩到断奶期间，给哺乳期母犬投喂铅，之后直接给幼犬投喂铅。报告了5只实验动物和4只对照动物的骨骼放射形态计量学和骨骼放射密度测定结果。尽管实验组的骨铅和血铅水平显著更高，但两组之间的股骨总长度、股骨干宽度，以及皮质厚度、厚度/宽度比和放射光密度测定值并无显著差异。
