Lange R D, Chen J P, Dunn C D
Exp Hematol. 1980;8 Suppl 8:197-224.
Published reports of the levels of erythropoietin (Ep) in normal human serum have been reviewed. Current evidence suggests that the level of Ep in normal human serum is 30 +/- 10 mU Ep/ml. When serum was concentrated before assay somewhat lower values were obtained and the mouse fetal liver cell assay gave slightly higher values. Three new potential Ep assay techniques are presented. These are: 1) The use of synthetic microbeads as indicators in an agglutination assay, 2) the use of wheat germ lectin in affinoelectrophoresis techniques, and 3) an immunoradiometric assay as an alternative to radioimmunoassays. The results indicate that the use of all three assays should be explored further.
已对已发表的关于正常人血清中促红细胞生成素（Ep）水平的报告进行了综述。目前的证据表明，正常人血清中Ep的水平为30±10 mU Ep/ml。在测定前对血清进行浓缩时，得到的值略低，而小鼠胎肝细胞测定法给出的值略高。介绍了三种新的潜在Ep测定技术。它们是：1）在凝集试验中使用合成微珠作为指示剂，2）在亲和电泳技术中使用麦胚凝集素，3）作为放射免疫测定替代方法的免疫放射测定法。结果表明，这三种测定方法都应进一步探索。
