Ciman M, Caldesi Valeri V, Siliprandi N
Int J Vitam Nutr Res. 1978;48(2):177-81.
The acetylcarnitine/carnitine ratio has been found significantly increased in tibial muscles of swimming rats in comparison with normal rats. Analogous increase occurred in electrically stimulated tibial muscle in comparison with the unstimulated controlateral muscle of the same animal. Swimming also induced a statistically significant increase of the acetylcarnitine/carnitine ratio in heart, while norepinephrine administration resulted in a decrease of carnitine not accompanied by a corresponding increase in acetylcarnitine in a severe carnitine depletion of cardiac muscle. These results are discussed in terms of carnitine function in the acetyl metabolism, assuming the acetylcarnitine as a possible acetyl reservoir in the working muscle.
与正常大鼠相比，已发现游泳大鼠胫骨肌肉中的乙酰肉碱/肉碱比值显著升高。与同一只动物未受刺激的对侧肌肉相比，电刺激的胫骨肌肉中也出现了类似的升高。游泳还导致心脏中乙酰肉碱/肉碱比值有统计学意义的升高，而在严重的心肌肉碱缺乏情况下，给予去甲肾上腺素会导致肉碱减少，而乙酰肉碱却没有相应增加。假设乙酰肉碱是工作肌肉中可能的乙酰储存库，就肉碱在乙酰代谢中的功能对这些结果进行了讨论。
