Stanisic T, Sadlowski R, Lee C, Grayhack J T
Invest Urol. 1978 Jul;16(1):15-8.
Ventral prostates from adult Sprague-Dawley rats were removed at intervals during the first 2 weeks postcastration. Incubation of tissue with 3H-uridine and 3H-leucine was performed to determine the incorporation rate of radioactivity into the RNA and protein fractions respectively. Prostatic wet weight and 3H-leucine incorporation rate into prostate protein diminished postcastration, whereas 3H-uridine incorporation rate remained relatively high. The data suggest that RNA synthesis is relatively active in comparison with other parameters during regression.
在成年Sprague-Dawley大鼠去势后的前2周内，每隔一段时间切除其腹侧前列腺。分别用³H-尿苷和³H-亮氨酸孵育组织，以测定放射性分别掺入RNA和蛋白质组分的速率。去势后前列腺湿重和³H-亮氨酸掺入前列腺蛋白质的速率降低，而³H-尿苷掺入速率仍相对较高。数据表明，在前列腺退化过程中，与其他参数相比，RNA合成相对活跃。
